Brew Better Beer
For thousands of years, ale-type beers have been brewed with Saccharomyces cerevisiae
(brewer's or baker's yeast). In contrast, lager beer, which utilizes
fermentations carried out at much lower temperature than for ale, is a
more recently developed alcoholic beverage, appearing in Bavaria near
the end of the Middle Ages. Lager beer gained worldwide popularity
starting in the late 1800s, when the advent of refrigeration made
year-round low-temperature fermentations possible. Saccharomyces pastorianus, the yeast used in lager brewing, is a "hybrid" organism of two yeast species, Saccharomyces bayanus and S. cerevisiae.
It is thought that the contributions of both parent species resulted
in an organism able to out-compete other yeasts during the cold lager
fermentations.
Though early brewers understood that different brewing conditions
would produce a unique beer, scientists are now unlocking the genetic
differences between yeast strains that produce variation in flavor,
color, and aroma. By comparing the genomic properties of yeast strains
sampled from breweries around the world, Drs. Barbara Dunn and Gavin
Sherlock of Stanford University have measured the genetic contribution
of the parent yeasts to strains of S. pastorianus and revealed new insights into the events that brought about the evolution of lager yeast.
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